A reproducible, cloud-scale reanalysis of five peer-reviewed studies on cellular aging, reprogramming, and rejuvenation, and an honest account of what survived contact with a shared pipeline.
What happens when a bioreactor engineer points his state-estimation toolkit at football. Model90 is a statistical forecasting engine for the 2026 World Cup and the major leagues, built on Dixon-Coles Poisson, Elo, xG and a calibrated meta-model. An honest look at how it works and what its Brier score really means.
Single-cell RNA sequencing is one of those techniques that generates a huge amount of data and then demands a huge amount of effort to interpret it. You run the sequencer, get a matrix of 20,000 genes by several thousand cells, and then spend the next several days (or weeks) figuring out what’s in there. I… Read More: I Built a Single-Cell RNA-seq Pipeline That Writes Its Own… »
I rebuilt two published CHO cell-culture papers — a hybrid ODE + machine-learning growth model, and a genome-scale metabolic reduction pipeline — as an interactive digital twin that runs in the browser. Here’s how it works, what’s under the hood, and an honest take on what it’s good for. No hosted version yet; the code is on GitHub and a live instance is coming soon.
The Features That Matter After training the developability model on 100+ therapeutic antibodies, I looked at the feature importance rankings. The model had learned to weight certain properties more heavily than others when making predictions. Some of these were obvious. Some were surprising. All of them tell us something about what actually makes antibodies difficult… Read More: What Makes an Antibody Hard to Manufacture? Data-Driven Insights »
A bioprocess engineer’s journey into machine learning and why the pharmaceutical industry desperately needs this bridge When I tell people I work in bioprocess engineering, I usually get blank stares. When I explain that I help manufacture proteins in giant tanks for therapeutic use, the response is often: “Oh, like brewing beer?” Not quite. But… Read More: How I Built a Machine Learning Tool to Predict Drug… »