Category Archives: Biotechnology

What Makes an Antibody Hard to Manufacture? Data-Driven Insights

By | January 25, 2026

The Features That Matter After training the developability model on 100+ therapeutic antibodies, I looked at the feature importance rankings. The model had learned to weight certain properties more heavily than others when making predictions. Some of these were obvious. Some were surprising. All of them tell us something about what actually makes antibodies difficult… Read More: What Makes an Antibody Hard to Manufacture? Data-Driven Insights »

Case Study: Predicting Trastuzumab Developability

By | January 25, 2026

Why Trastuzumab Is the Perfect Test Case When I built my antibody developability predictor, I knew I needed to validate it against a molecule where we actually know the manufacturing story. Trastuzumab (Herceptin) was the obvious choice. It’s one of the most successful therapeutic antibodies ever made, with decades of manufacturing data behind it. More… Read More: Case Study: Predicting Trastuzumab Developability »

From Conventional Design to AI-Driven Innovation: A Strategic Journey in Advanced Manufacturing

By | January 24, 2026

The Inflection Point Three-four years ago, I stood in front of production equipment I’d designed using textbook equations and decades-old heuristics. The systems worked—they always had—but I couldn’t shake the feeling that we were leaving performance on the table. That nagging intuition led me down a rabbit hole of machine learning papers, Python tutorials, and… Read More: From Conventional Design to AI-Driven Innovation: A Strategic Journey in… »